1. Xu G, Ding Q, Zhang YF et al. Intravesical instillation of sodium hyaluronate for the treatment of intractable non-bacterial cystitis: a multi-centre study. Presented at the 1st Annual Meeting of MICA, Rome, 21-22 September, 2004.

2. Engelhardt PF, Morakis N, Daha LK et al. Long-term results of intravesical hyaluronan therapy in Bladder Pain Syndrome/Interstitial Cystitis. Int Urogynecol J 2011;22:401-405.

3. Constantinides C, Manousakas T, Nikolopoulos P et al. Prevention of recurrent bacterial cystitis by intravesical administration of hyaluronic acid: a pilot study. Br J Urol lnt 2004;93:1262-1266.

4. Delgado Perez JM, Samper P & Garrido JS. Hyaluronic acid in the prevention of radiation-induced cystitis. Proc Am Soc Clin Oncol 2003;22.

17. Moutzouris DA, Falagas ME. Interstitial cystitis: An unsolved enigma. Clin J Am Soc Nephrol 2009;4:1844-1857.

18. Payne H, Adamson A, Bahl A et al. Chemical- and radiation-induced haemorrhagic cystitis: current treatments and challenges. BJU Int 2013;112:885-897.

What is Cystistat for?

Cystistat is effective where the lining of the bladder is compromised and symptoms are moderate or severe1,2,3,4

Interstitial Cystitis

  • Its cause is unknown but it is thought to result from a chronic inflammation and degeneration of the bladder wall17
  • It does not respond to conventional antibiotic therapy17
  • It is also known as Painful Bladder Syndrome (PBS)

Recurrent Bacterial Cystitis

  • Repeated urinary tract infection (UTI) caused by bacteria entering the bladder, resulting in the inflammation and degeneration of the bladder wall

It has been suggested that reversing the damage by temporarily replacing the glycosaminoglycan (GAG) layer results in control of symptoms3

Radiation-induced Cystitis

  • Haemorrhagic cystitis (HC) has been reported in up to 20% of patients treated with radiotherapy to the pelvic area18
  • In severe cases, HC is associated with significant morbidity, prolonged hospitalisation and occasional mortality18